Hey Axes do you think this trend is applicable to other non-traditional matchups in other lanes, like Seraphine and Ziggs bot or Vayne going top?
Certainly for at least some of them, but not necessarily with the same implications for game balance. Bot carry very likely has a related pattern with the set of mages who tend to counter ADCs, for example, since nearly every matchup is vs an ADC.
Using Pantheon as an example, his mid lane win rate appears to (and there are LARGE caveats on this analysis, so I emphasize "appears to") be inflated because he is both sharp in terms of who he counters and is countered by AND because the things he sharply counters are so much more popular than the things he is countered by. If every champion was exactly equally popular, his average win rate would very likely fall quite a bit in that position even with no gameplay changes.
(The inverse pattern is found on Akshan - his mid lane win rate is depressed by the fact that Yasuo is very strong counter to him, which gives him the appearance of being better top lane sometimes)
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